We are pleased to invite you to the 20th Seminar of HITRIplus, which will take place on Wednesday, 1 October 2025, from 17:00 to 18:00 CEST.
Speaker: Dr Daria Boscolo (GSI, Darmstadt)
Title: Radioactive Ion Beams for Image-Guided Particle Therapy & Biomedical Applications
The seminar will address how radioactive ion beams (RIBs), with their β⁺-decay and PET imaging potential, may enable real-time monitoring during charged particle therapy.
Dr Boscolo will present recent achievements in accelerator technology and preclinical studies, including the first mouse tumour treatment with RIBs, and discuss challenges in dosimetry, radiobiology, and imaging performance.
Daria Boscolo, PhD, is a Staff Physicist in the Biophysics department at GSI (Darmstadt), where she works as Deputy Group Leader in the Particle Therapy Physics group. She studied physics at the University of Pisa and obtained her doctorate at TU Darmstadt. Her research focuses on the interaction of charged particle radiation and its applications for space radiation protection and for the development of advanced particle therapy applications. Recently, she investigated the use of radioactive ion beams for combined cancer therapy and real-time imaging in the context of the Biomedical Application of Radioactive Ion Beams (BARB) project. In this seminar, she will give an overview of this work, focusing on the more recent preclinical studies.
Radioactive Beams for Image-Guided Particle Therapy and biomedical applications 45m
While charged particle therapy is among the most advanced radiotherapy techniques, its clinical potential is still limited by uncertainties in the beam range. Radioactive ion beams (RIBs) have been proposed for decades as a way to address this limitation, since isotopes undergoing β⁺-decay can be directly visualized through positron emission tomography (PET). This unique property offers the possibility of combining treatment and real time range monitoring. Until recently, the challenging production and the limited intensities of RIBs have hindered their translation into a clinical setting. Recent progress in accelerator technology now makes it possible to generate RIBs with sufficient intensities for systematic preclinical investigations. Within this framework, the BARB (Biomedical Applications of Radioactive ion Beams) initiative at GSI explores the biological and physical aspects of RIBs, from dosimetry to radiobiological effectiveness and imaging performance. In this seminar, an overview of the current status of RIBs research GSI will we be presented with a particular focus on the latest results on the first treatment of a mouse tumor by radioactive ion beams.
Full details & Zoom link: https://indico.cern.ch/event/1586839/
We look forward to your participation and a lively discussion. Please feel free to share this announcement within your networks.